Recent Publications

Recent publications by members of the SREMI team (Nov 2019 - Oct 2020)

Geriatric EM (n=16) 

  1. Tate K, Reid RC, McLane P, Cummings GE, Rowe BH, Estabrooks CA, Norton P, Lee JS, Wagg A, Robinson C, Cummings GG. Who Doesn’t Come Home? Factors Influencing Mortality Among Long-Term Care Residents Transitioning to and From Emergency Departments in Two Canadian Cities. J Appl Gerontol. 2020 Oct 7:733464820962638. doi: 10.1177/0733464820962638. Epub ahead of print. 
  2. Dahlstrom EB, Han JH, Healy H, Kennedy M, Arendts G, Lee J, Carpenter C, Lee S. Delirium prevention and treatment in the emergency department (ED): a systematic review protocol. BMJ Open. 2020 Oct 6;10(10):e037915. doi: 10.1136/bmjopen-2020-037915. 
  3. Eagles D, Ellis B, Melady D. Frailty: A key concept to improve older person care. CJEM. 2020 Sep;22(5):624-625.
  4. Lanoue MP, Sirois MJ, Perry JJ, Lee J, Daoust R, Worster A, Hegg S, Carmichael PH, Brousseau-Turcotte AA, Émond M. Fear of falling in community-dwelling older adults presenting to the emergency department for minor injuries: Impact on return to the ED and future falls. CJEM. 2020 Sep;22(5):692-700.
  5. Archambault PM, Rivard J, Smith PY, Sinha S, Morin M, LeBlanc A, Couturier Y, Pelletier IMelady D, Ghandour EK, Légaré F, Denis JL, , Paré D, Chouinard J, Kroon C, Huot-Lavoie M, Bert L, Witteman HO, Brousseau AA, Dallaire C, Sirois MJ, Émond M, Fleet R, Chandavong S; Network Of Canadian Emergency Researchers. Learning Integrated Health System to Mobilize Context-Adapted Knowledge with a Wiki Platform to Improve the Transitions of Frail Seniors From Hospitals and Emergency Departments to the Community (LEARNING WISDOM): Protocol for a Mixed-Methods Implementation Study. JMIR Res Protoc. 2020 Aug 5;9(8):e17363. doi: 10.2196/17363.
  6. Ellis B, Melady D, Foster N, Sinha S, Lau V, Saraga S, McLeod SL. Using volunteers to support older people in the emergency department: experience from a Canadian tertiary care hospital. CJEM. 2020 Jul;22(4):514-518.
  7. de Wit K, Parpia S, Varner C, Worster A, McLeod SL, Clayton N, Kearon C, Mercuri M. Clinical predictors of intracranial bleeding in older adults who have fallen: a cohort study. J Am Geriatr Soc. 2020 May;68(5):970-976.
  8. Rose L, Agar M, Burry L, Campbell N, Clarke M, Lee J, Marshall J, Siddiqi N, Page V; Development of Core Outcome Sets for Effectiveness Trials of Interventions to Prevent and/or Treat Delirium (Del-COrS) Group. Reporting of outcomes and outcome measures in studies of interventions to prevent and/or treat delirium in the critically ill: A systematic review. Crit Care Med. 2020 Apr;48(4):e316-e324. doi: 10.1097/CCM.0000000000004238.
  9. Mercier É, Nadeau A, Brousseau AA, Émond M, Lowthian J, Berthelot S, Costa AP, Mowbray F, Melady D, Yadav K, Nickel C, Cameron PA. Elder abuse in the out-of-hospital and emergency department settings: A scoping review. Ann Emerg Med. 2020 Feb;75(2):181-191.
  10. HIP ATTACK Investigators (Lee JS). Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. Lancet. 2020 Feb 29;395(10225):698-708.
  11. Rosen T, Liu SW, Cameron-Comasco L, Clark S, Mulcare MR, Biese K, Magidson PD, Tyler KR, Melady D, Thatphet P, Wongtangman T, Elder NM, Stern ME; Academy of Geriatric Emergency Medicine. Geriatric Emergency Medicine Fellowships: Current State of Specialized Training for Emergency Physicians in Optimizing Care for Older Adults. AEM Educ Train. 2020 Jan 21;4(Suppl 1):S122-S129. doi: 10.1002/aet2.10428. eCollection 2020 Feb.
  12. Mowbray F, Brousseau AA, Mercier E, Melady D, Émond M, Costa AP. Examining the relationship between triage acuity and frailty to inform the care of older emergency department patients: Findings from a large Canadian multisite cohort study. CJEM. 2020 Jan;22(1):74-81.
  13. Ringer T, Thompson C, McLeod SL, Melady D. Inter‐rater agreement between self‐rated and staff‐rated clinical frailty scale scores in older emergency department patients: A prospective observational study. Acad Emerg Med. 2020;27(5):419‐422.
  14. Lee JS, Tong T, Tierney MC, Kiss A, Chignell M. Predictive Ability of a Serious Game to Identify Emergency Patients With Unrecognized Delirium. J Am Geriatr Soc. 2019 Nov;67(11):2370-2375.
  15. Boucher V, Lamontagne ME, Lee J, Carmichael PH, Déry J, Émond M. Acceptability of older patients’ self-assessment in the Emergency Department (ACCEPTED)-a randomised cross-over pilot trial. Age Ageing. 2019 Nov 1;48(6):875-880.
  16. de Vries M, Gravel J, Horn D, McLeod S, Varner C. Comparative efficacy of opioids for older adults presenting to the emergency department with acute pain: Systematic review. Can Fam Physician. 2019 Dec;65(12):e538-e543.

COVID-19 (n=10)

  1. Varner C. Hospitals rolling out the “welcome mat” to ease COVID-19 fears. CMAJ. 2020 Oct 5;192(40):E1171-E1172. doi: 10.1503/cmaj.1095898. 
  2. Glicksman R, Varner C. Chilblain-like lesions likely associated with coronavirus disease 2019: A Canadian case presentation. CJEM. 2020 Sep;22(5):611-613.
  3. Siemieniuk RAC, Bartoszko JJ, Ge L, Zeraatkar D, Rochwerg B, Lamontagne F, Han MA, Kum E, Liu Q, Agarwal A, Agoritsas T, Alexander P, Cheung K, Chu DK, Couban R, Devji T, Fang B, Fang C, Flottorp SA, Foroutan F, Heels-Ansdell D, Pardo-Hernandez H, Honarmand K, Hou X, Ibrahim Q, Izcovich A, Loeb M, Marcucci M, McLeod SL, Motaghi S, Murthy S,  Mustafa RA, Neary JD, Rada G, Riaz IB, Sadeghirad B, Sekercioglu N, Sheng L, Switzer C, Tendal B, Thabane L, Tomlinson G, Turner T, Vandvik PO, Vernooij RWM, Viteri-García A, Wang Y, Yao L, Ye Z, Guyatt GH, Brignardello-Petersen R. Drug treatments for covid-19: living systematic review and network meta-analysis. BMJ. 2020 Jul 30;370:m2980. doi: 10.1136/bmj.m2980.
  4. Wright J, Tan D, Walmsley SL, Hulme J, O’Connor E, Snider C, Cheng I, Chan AK, Borgundvaag B, McLeod SL, Gollob M, Clarke RJ, Dresser L, Haji F, Mazzulli M, Mubareka S, Juni P, Lee D, Tomlinson G, Kain K, Landes M. Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada. Trials. 2020 Jul 14;21(1):647.
  5. Varner C. Pandemic advances alternatives to hallway medicine. CMAJ. 2020 Jul 6;192(27):E789-E790.
  6. Lang E, Ovens H, Schull MJ, Snider C. Authentic emergency department leadership during a pandemic. CJEM. 2020 Jul;22(4):400-403. 
  7. Mohindra R, Atlin C, Moran C, Shook A, Ennis A, Page J, Vaglica M, Hannam P. Coronavirus disease - 2019 assessment zone: A community hospital’s rapid response to a novel infectious pandemic. CJEM. 2020 May 8:1-2
  8. Varner C. Parents on the front lines of COVID-19 face tough choices. CMAJ. 2020 Apr 27;192(17):E467-E468.
  9. Boreskie KF, Boreskie PE, Melady D. Age is just a number - and so is frailty: Strategies to inform resource allocation during the COVID-19 pandemic. CJEM. 2020  Jul;22(4):411-413.
  10. Levine S, Bonner A, Perry A, Melady D, Unroe KT. COVID-19 in Older Adults: Transfers Between Nursing Homes and Hospitals. JGEM. 2020 Mar 27:1;5.

Cardiovascular (n=10)

  1. Cheskes S, McLeod SL, Nolan M, Snobelen P, Vaillancourt C, Brooks S, Dainty KN, Chan T, Drennan IR. Improving access to automated external defibrillators in rural and remote settings: A drone delivery Feasibility Study. JAHA. 2020 Jul 4;e016687.
  2. Cheskes S, Dorian P, Feldman M, McLeod SL, Scales DC, Pinto R, Turner L, Morrison LJ, Drennan IR, Verbeek PR. Double Sequential External Defibrillation. Resuscitation. 2020; Jul;152:214.
  3. Mohindra R, Lin S. The drugs don’t matter: Cardiovascular drugs have minimal effects on amplitude spectral area during ventricular fibrillation. Resuscitation. 2020Jun;151:205-207.
  4. Cheskes S, Dorian P, Feldman M, McLeod SL, Scales DC, Pinto R, Turner L, Morrison LJ, Drennan IR, Verbeek PR. Double Sequential External Defibrillation for Refractory Ventricular Fibrillation: The DOSE VF Pilot Randomized Controlled Trial. Resuscitation. 2020 May; 150:178-184.
  5. Sem M, Lin S, Reading J, Mohindra R. The need to review knowledge gaps on sudden cardiac death in Canadian indigenous populations. CJEM. 2020 May;22(3):E5. doi: 10.1017/cem.2020.26.
  6. Wu W, Chopra A, Ziegler C, McLeod SL, Lin S. Predictive value of hospital discharge neurological outcome scores for long-term neurological status following out-of-hospital cardiac arrest: a systematic review. Resuscitation. 2020 Apr 15;151:139-144.
  7. Nosrati R, Lin S, Mohindra R, Ramadeen A, Toronov V, Dorian P. Study of the effects of epinephrine on cerebral oxygenation and metabolism during cardiac arrest and resuscitation by hyperspectral near-infrared spectroscopy. Crit Care Med. 2019 Apr;47(4):e349-e357.
  8. Stiell IG, Sivilotti MLA, Taljaard M, Birnie D, Vadeboncoeur A, Hohl CM, McRae AD, Rowe BH, Brison RJ, Thiruganasambandamoorthy V, Macle L, Borgundvaag B, Morris J, Mercier E, Clement CM, Brinkhurst J, Sheehan C, Brown E, Nemnom MJ, Wells GA, Perry JJ. Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibrillation (RAFF2): a partial factorial randomised trial. Lancet. 2020 Feb 1;395(10221):339-349.
  9. Mohindra R, Patel M, Lin S. A new paradigm of resuscitation: Perfusion-guided cardiopulmonary resuscitation. Resuscitation. 2019 Feb;135:230-231.
  10. Teefy J, Cram N, van Zyl T, VanAarsen K, McLeod SL, Dukelow A. Evaluation of the uptake of a pre-hospital cardiac arrest termination of resuscitation rule. J Emerg Med. 2020 Feb;58(2):254-259.

General EM (n=10)

  1. Balzer N, McLeod SL, Walsh C, Grewal K. Low-dose ketamine for acute pain control in the emergency department: A systematic review and meta-analysis. Acad Emerg Med. 2020 Oct 24. doi: 10.1111/acem.14159. Epub ahead of print.
  2. Émond M Artz J, Morrison LJ, Snider CE, McLeod SL, LeSage N, Stiell IG, Perry JJ. An environmental scan of emergency medicine research support, training, and infrastructure across Canada. CJEM. 2020 Jul;22(4):477-485.
  3. Borgundvaag B, Klaiman M. Management of alcohol withdrawal: time to “SHAKE” things up? CJEM. 2020 Mar;22(2):131-132. doi: 10.1017/cem.2020.7.
  4. Berezin L, Thompson C, Rojas-Luengas V, Borgundvaag B, McLeod SL. Lumbosacral Spinal Imaging for Patients Presenting to the Emergency Department with Nontraumatic Low Back Pain. J Emerg Med. 2020 Feb;58(2):269-274.
  5. Taher A, Bunker E, Chartier LB, Ostrow O, Ovens H, Davis B, Schull MJ. Application of the Informatics Stack framework to describe a population-level emergency department return visit continuous quality improvement program. Int J Med Inform. 2020 Jan;133:103937.
  6. Stewart E, Grewal K, Hudson H, Thompson M, Godwin J. Clinical characteristics and outcomes associated with bupropion overdose: a Canadian perspective. Clin Toxicol (Phila). 2019 Dec 12:1-6.
  7. Peng S, Micks T, Braganza D, Sue K, Woo M, Rogers P, Freedman S, Lewis J, Hu S, Varner C, Patel N, Hameed S, Steinmetz P. Canadian national survey of family medicine residents on point-of-care ultrasound training. Can Fam Physician. 2019 Dec;65(12):e523-e530.
  8. Cargnelli S, Thompson C, Dear T, Sandre A, Borgundvaag B, McLeod SL. The prevalence of pathological findings identified by next day abdominal ultrasound in patients discharged from the emergency department. CJEM. 2019 Nov;21(6):793-797.
  9. Varner CE. Specialized concussion clinic referrals are not intended for all acute concussion patients in the emergency department. CJEM. 2019 Nov;21(6):694-697.
  10. Glanz S, Ellis B, McLeod SL, Thompson C, Melady D, Nelson M. Volunteer Contributions in the Emergency Department: A Scoping Review. Patient Exp J. 2019;6(3):105-113. 

Early Pregnancy (n=4)

  1. Glicksman R, Varner C, McLeod SL, Page A, Thomas J. Exploring the services and management available to women experiencing complications in early pregnancy: A survey of Ontario hospitals. J Obstet Gynaecol. 2020 Apr 24:1-5. doi: 10.1080/01443615.2020.1725453. Online ahead of print. 
  2. Varner CE, Park AL, Little D, Ray JG. Emergency department use by pregnant women in Ontario: a retrospective population-based cohort study. CMAJ Open. 2020 Apr 28;8(2):E304-E312. 
  3. Varner C. Ontario ponders expanded prescribing by midwives. CMAJ. 2020 Mar 16;192(11):E293-E294. doi: 10.1503/cmaj.1095853.
  4. Rojas-Luengas V, Seaton B, Dainty K, McLeod S, Varner C. The emergency department experience of patients with early pregnancy complications: A qualitative study. CJEM. 2019 Nov;21(6):798-802.

Triage and Flow (n=4)

  1. Rowe BH, Ovens H, Schull MJ. CJEM Debate Series: #EDRedirection - Efforts to divert patients from the emergency department - Stop blaming the patients! An argument against redirection. CJEM. 20F20 Sep;22(5):641-643.
  2. McLeod SL, Thompson C, Borgundvaag B, Thabane L, Ovens H, Scott S, Ahmed T, Grewal K, McCarron J, Filsinger B, Mittmann N, Worster A, Agoritsas T, Bullard M, Guyatt G. Consistency of triage scores by presenting complaint pre and post-implementation of a real time electronic triage decision-support tool. JACEP Open. 2020. 2020;1:747–756
  3. McLeod SL, McCarron J, Ahmed T, Grewal K, Mittmann N, Scott S, Ovens H, Garay J, Bullard M, Rowe BH, Dreyer J, Borgundvaag B. Interrater reliability, accuracy and triage time pre and post-implementation of a real time electronic triage decision-support tool. Ann Emerg Med. 2020 Apr;75(4):524-531. 
  4. Agnihotri T, Fan M, McCarron J, McLeod SL, Borgundvaag B, Ovens H, Trbovich P. The impact of an electronic decision support system on nursing triage process: A usability and workflow analysis. Can J Nurs Res. 2020 Jan 21:844562119893514. doi: 10.1177/0844562119893514. [Epub ahead of print]. 

Cancer (n=2)

  1. Grewal K, Krzyzanowska M, McLeod SL, Borgundvaag B, Atzema C. Outcomes after emergency department use in patients with cancer receiving chemotherapy in Ontario, Canada: A population based cohort study. CMAJ Open. 2020 Aug 12;8(3):E496-E505.
  2. Grewal K, Munshi L, Krzyzanowska MK. Just the Facts: Adverse events associated with immune checkpoint inhibitor treatment for cancer. CJEM. 2020 Jun 29:1-4.