Recent Publications

Recent publications by members of the SREMI team (Nov 2020 - Oct 2021)

Geriatric EM (n=10) 

  1. Carpenter CR, Hammouda N, Linton EA, Doering M, Ohuabunwa UK, Ko KJ, Hung WW, Shah MN, Lindquist LA, Biese K, Wei D, Hoy L, Nerbonne L, Hwang U, Dresden SM; GEAR Network. Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A Geriatric Emergency Care Applied Research (GEAR) Network Scoping Review and Consensus Statement. Acad Emerg Med. 2021 Jan;28(1):19-35. 
  2. Selvanayagam N, Mowbray F, Clayton N, Soomroo A, Varner C, McLeod SL, de Wit K. Reliability of patient-reported major bleeding, anticoagulation and antiplatelet status. Res Pract Thromb Haemost. 2021 Mar 26;5(4):e12501.
  3. Kayser J, Morrow-Howell N, Rosen TE, Skees S, Doering M, Clark S, Hurka-Richardson K, Bin Shams R, Ringer T, Hwang U, Platts-Mills TF. Research priorities for elder abuse screening and intervention: A Geriatric Emergency Care Applied Research (GEAR) network scoping review and consensus statement. J Elder Abuse Negl. Mar-May 2021;33(2):123-144.
  4. Boucher V, Lamontagne ME, Lee J, Émond M. Self-assessment of functional status in older emergency department patients: a cross-over randomized pilot trial. CJEM. 2021 May;23(3):337-341.
  5. Rose L, Burry L, Agar M, Blackwood B, Campbell NL, Clarke M, Devlin JW, Lee J, Marshall JC, Needham DM, Siddiqi N, Page V. A core outcome set for studies evaluating interventions to prevent and/or treat delirium for adults requiring an acute care hospital admission: an international key stakeholder informed consensus study. BMC Med. 2021 Jun 18;19(1):143. 
  6. de Wit K, Mercuri M, Clayton N, Worster A, Mercier E, Emond M, Varner C, McLeod SL, Eagles D, Stiell I, Barbic D, Morris J, Jeanmonod R, Kagoma Y, Shoamanesh A, Engels PT, Sharma S, Kearon C, Papaioannou A, Parpia S; Network of Canadian Emergency Researchers. Which older emergency patients are at risk of intracranial bleeding after a fall? A protocol to derive a clinical decision rule for the emergency department. BMJ Open. 2021 Jul 2;11(7):e044800. 
  7. Lee JS, Bhandari T, Simard R, Emond M, Topping C, Woo M, Perry J, Eagles D, McRae AD, Lang E, Wong C, Sivilotti M, Newbigging J, Borgundvaag B, McLeod SL, Melady D, Chernoff I, Kiss A, Chenkin J. Point-of-care ultrasound-guided regional anaesthesia in older ED patients with hip fractures: a study to test the feasibility of a training programme and time needed to complete nerve blocks by ED physicians after training. BMJ Open. 2021 Jul 5;11(7):e047113. 
  8. Ellis B, Lowthian JA, Melady D. IFEM White Paper on the care of older people with acute illness and injury in the emergency department. CJEM. 2021 Jul;23(4):425-426.
  9. Rose L, Burry L, Agar M, Campbell NL, Clarke M, Lee J, Marshall JC, Devlin JW, Blackwood B, Needham DM, Siddiqi N, Page V; Del-COrS Group. A Core Outcome Set for Research Evaluating Interventions to Prevent and/or Treat Delirium in Critically Ill Adults: An International Consensus Study (Del-COrS). Crit Care Med. 2021 Sep 1;49(9):1535-1546.
  10. Grewal K, Atzema CL, Austin PC, de Wit, MD K, Sharma S, Mittmann N, Borgundvaag B, McLeod SL. Risk of intracranial hemorrhage between direct oral anticoagulants in older patients seen in the emergency department with a head injury: A population-based cohort study. CMAJ October 12, 2021 193 (40) E1561-E1567; DOI: https://doi.org/10.1503/cmaj.210811.

GENERAL EM (n=10)

  1. Forristal C, Hayman K, Smith N, Mal S, Columbus M, Farooki N, Van Aarsen K, McLeod SL, Ouellette D. Does utilization of an intubation safety checklist reduce dangerous omissions during simulated resuscitation scenarios: A multi-center randomized controlled trial. CJEM. 2021 Jan;23(1):45-53.
  2. Zarabi S, Chan TM, Mercuri M, Kearon C, Turcotte M, Grusko E, Barbic D, Varner C, Bridges E, Houston R, Eagles D, de Wit K. Physician choices in pulmonary embolism testing. CMAJ. 2021. Jan 11;193(2):E38-E46. 
  3. Perry JJ, Vaillancourt C, Hohl CM, Thiruganasambandamoorthy V, Morris J, Emond M, Lee J, Stiell IG. Optimizing collaborative relationships in emergency medicine research. CJEM. 2021 May;23(3):291-296.
  4. Davis PJ, Yan J, de Wit K, Archambault PM, McRae A, Savage DW, Poonai N, Sivilotti MLA, Carter A, McLeod SL. Starting, building and sustaining a program of research in emergency medicine in Canada. CJEM. 2021. May;23(3):297-302
  5. Sheridan C, Cirone J, Grewal K, Tejpar Q, Lacombe S. Barbeque Brush Bristle Ingestion. J Emerg Med. 2021 Jan 29:S0736-4679(20)31363-9. doi: 10.1016/j.jemermed.2020.12.015. Epub ahead of print. 
  6. Sheridan C, Grewal K, Thomson C, Borgundvaag B, McLeod SL. Antibiotic prescribing and use of corticosteroids for the emergency department management of acute uncomplicated pharyngitis in adult patients. Fam Pract. 2021 Jun 26:cmab035. doi: 10.1093/fampra/cmab035. Online ahead of print.\
  7. Shillington K, Thompson C, Saraga S, Soch L, Asomaning N, Borgundvaag B, McLeod SL. The Effect of a Nurse Initiated Therapeutic Conversation Compared to Standard Care for Patients With Acute Pain in the ED: A Randomized Controlled Trial. Adv Emerg Nurs J. 2021 Jul-Sep 01;43(3):217-224. 
  8. Drummond A, Chochinov A, Johnson K, Kapur A, Lim R, Ovens H. CAEP position statement on violence in the emergency department. CJEM. 2021 Aug 5. doi: 10.1007/s43678-021-00182-z. Epub ahead of print. 
  9. Grewal K, Atzema CL, Sutradhar R, Everett K, Horner D, Thompson C, Theodoropoulos J, Borgundvaag B, McLeod SL, de Wit K. Venous Thromboembolism in Patients Discharged From the Emergency Department With Ankle Fractures: A Population-Based Cohort Study. Ann Emerg Med. 2021 Sep 14:S0196-0644(21)00517-5. doi: 10.1016/j.annemergmed.2021.06.017. Epub ahead of print.
  10. Gregory C, Chorny Y, McLeod SL, Mohindra R. First-line Medications for the Outpatient Treatment of Alcohol Use Disorder: A Systematic Review of Perceived Barriers. J Addict Med. 2021 Sep 22. Epub ahead of print.
     

Cardiovascular (n=9)

  1. Drennan IR, Dorian P, McLeod SL, Pinto R, Scales DC, Turner L, Feldman M, Verbeek PR, Morrison LJ, Cheskes S. DOuble SEquential External Defibrillation for Refractory Ventricular Fibrillation (DOSE VF): study protocol for a randomized controlled trial. Trials. Trials. 2020 Nov 26;21(1):977.
  2. Perry JJ, Sivilotti MLA, Émond M, Stiell IG, Stotts G, Lee J, Worster A, Morris J, Cheung KW, Jin AY, Oczkowski WJ, Sahlas DJ, Murray HE, Mackey A, Verreault S, Camden MC, Yip S, Teal P, Gladstone DJ, Boulos MI, Chagnon N, Shouldice E, Atzema C, Slaoui T, Teitlebaum J, Abdulaziz K, Nemnom MJ, Wells GA, Sharma M. Prospective validation of Canadian TIA Score and comparison with ABCD2 and ABCD2i for subsequent stroke risk after transient ischaemic attack: multicentre prospective cohort study. BMJ. 2021 Feb 4;372:n49.
  3. Stiell IG, Sivilotti MLA, Taljaard M, Birnie D, Vadeboncoeur A, Hohl CM, McRae AD, Morris J, Mercier E, Macle L, Brison RJ, Thiruganasambandamoorthy V, Rowe BH, Borgundvaag B, Clement CM, Brinkhurst J, Brown E, Nemnom MJ, Wells GA, Perry JJ. A randomized, controlled comparison of electrical versus pharmacological cardioversion for emergency department patients with acute atrial flutter. CJEM. 2021 May;23(3):314-324. 
  4. Mohindra R, Cheskes S. Look through and see: validation of a CPR artifact removal algorithm for AEDs used in OHCA. Resuscitation. 2021. May;162:415-416.
  5. Calder LA, Perry J, Yan JW, De Gorter R, Sivilotti MLA, Eagles D, Myslik F, Borgundvaag B, Émond M, McRae AD, Taljaard M, Thiruganasambandamoorthy V, Cheng W, Forster AJ, Stiell IG. Adverse events among emergency department patients with cardiovascular conditions: A multicenter study. Ann Emerg Med. 2021 Jun;77(6):561-574.
  6. Cheskes L, Cheskes S, McLeod SL. Is there a role for ECMO-facilitated resuscitation for the management of out-of-hospital cardiac arrest (OHCA) with refractory ventricular fibrillation (VF)? CJEM. 2021 Jul;23(4):574.
  7. Mohindra R, Agrawal DK, Thankam FG. Altered Vascular Extracellular Matrix in the Pathogenesis of Atherosclerosis. J Cardiovasc Transl Res. 2021 Jan 8. doi: 10.1007/s12265-020-10091-8. Epub ahead of print. 
  8. Cortel-LeBlanc MA, Sharma M, Cortel-LeBlanc A, Sivilotti MLA, Émond M, Stiell IG, Stotts G, Lee J, Worster A, Morris J, Cheung KW, Jin AY, Oczkowski WJ, Sahlas DJ, Murray HE, Mackey A, Verreault S, Camden MC, Yip S, Teal P, Gladstone DJ, Boulos MI, Chagnon N, Shouldice E, Atzema C, Slaoui T, Teitelbaum J, Abdulaziz KE, Wells GA, Taljaard M, Perry JJ. Predictors of neurologists confirming or overturning emergency physicians’ diagnosis of TIA or stroke. CJEM. 2021 Sep 1. doi: 10.1007/s43678-021-00181-0. Epub ahead of print. 
  9. Fernando SM, Di Santo P, Sadeghirad B, Lascarrou JB, Rochwerg B, Mathew R, Sekhon MS, Munshi L, Fan E, Brodie D, Rowan KM, Hough CL, McLeod SL, Vaillancourt C, Cheskes S, Ferguson ND, Scales DC, Sandroni C, Nolan JP, Hibbert B. Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets. Intensive Care Med. 2021 Oct;47(10):1078-1088.
     

COVID-19 (n=8)

  1. Varner C. Women experts underrepresented in pandemic coverage. CMAJ. 2021 Jan 25;193(4):E143-E144.
  2. Hohl CM, Rosychuk RJ, McRae AD, Brooks SC, Archambault P, Fok PT, Davis P, Jelic T, Turner JP, Rowe BH, Mercier É, Cheng I, Taylor J, Daoust R, Ohle R, Andolfatto G, Atzema C, Hayward J, Khangura JK, Landes M, Lang E, Martin I, Mohindra R, Ting DK, Vaillancourt S, Welsford M, Brar B, Dahn T, Wiemer H, Yadav K, Yan JW, Stachura M, McGavin C, Perry JJ, Morrison LJ; Canadian COVID-19 Emergency Department Rapid Response Network investigators and for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group. Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study. 2021 Mar 17;9(1):E261-E270.
  3. Varner C. Hospitals grappling with nurse exodus. CMAJ. 2021 Apr 19;193(16):E569-E570. doi: 10.1503/cmaj.1095934. 
  4. Bartoszko JJ, Siemieniuk RAC, Kum E, Qasim A, Zeraatkar D, Ge L, Han MA, Sadeghirad B, Agarwal A, Agoritsas T, Chu DK, Couban R, Darzi A, Devji T, Ghadimi M, Honarmand K, Izcovich A, Khamis A, Lamontagne F, Loeb M, Marcucci M, McLeod SL, Motaghi S, Murthy S, Mustafa RA, Neary JD, Pardo-Hernandez H, Rada G, Rochwerg B, Switzer C, Tendal B, Thabane L, Vandvik PO, Vernooij RWM, Viteri-García A, Wang Y, Yao L, Ye Z, Guyatt GH, Brignardello-Petersen. Prophylaxis against covid-19: living systematic review and network meta-analysis. BMJ 2021; 373:n949 doi:10.1136/bmj.n949. 
  5. Varner CE. In adults, NSAID use vs. nonuse in the past 4 mo was not linked to increased risk for COVID-19-related mortality. Ann Intern Med. 2021 May;174(5):JC58.
  6. Flores M, Dayan I, Roth H, Zhong A, Harouni A, Gentili A, Abidin A, Liu A, Costa A, Wood B, Tsai CS, Wang CH, Hsu CN, Lee CK, Ruan C, Xu D, Wu D, Huang E, Kitamura F, Lacey G, Corradi GCA, Shin HH, Obinata H, Ren H, Crane J, Tetreault J, Guan J, Garrett J, Park JG, Dreyer K, Juluru K, Kersten K, Rockenbach MABC, Linguraru M, Haider M, AbdelMaseeh M, Rieke N, Damasceno P, Silva PMCE, Wang P, Xu S, Kawano S, Sriswa S, Park SY, Grist T, Buch V, Jantarabenjakul W, Wang W, Tak WY, Li X, Lin X, Kwon F, Gilbert F, Kaggie J, Li Q, Quraini A, Feng A, Priest A, Turkbey B, Glicksberg B, Bizzo B, Kim BS, Tor-Diez C, Lee CC, Hsu CJ, Lin C, Lai CL, Hess C, Compas C, Bhatia D, Oermann E, Leibovitz E, Sasaki H, Mori H, Yang I, Sohn JH, Murthy KNK, Fu LC, de Mendonça MRF, Fralick M, Kang MK, Adil M, Gangai N, Vateekul P, Elnajjar P, Hickman S, Majumdar S, McLeod S, Reed S, Graf S, Harmon S, Kodama T, Puthanakit T, Mazzulli T, Lavor VL, Rakvongthai Y, Lee YR, Wen Y. Federated Learning used for predicting outcomes in SARS-COV-2 patients. Res Sq [Preprint]. 2021 Jan 8:rs.3.rs-126892. doi: 10.21203/rs.3.rs-126892/v1. 
  7. Dayan I, Roth HR, Zhong A, Harouni A, Gentili A, Abidin AZ, Liu A, Costa AB, Wood BJ, Tsai CS, Wang CH, Hsu CN, Lee CK, Ruan P, Xu D, Wu D, Huang E, Kitamura FC, Lacey G, de Antônio Corradi GC, Nino G, Shin HH, Obinata H, Ren H, Crane JC, Tetreault J, Guan J, Garrett JW, Kaggie JD, Park JG, Dreyer K, Juluru K, Kersten K, Rockenbach MABC, Linguraru MG, Haider MA, AbdelMaseeh M, Rieke N, Damasceno PF, E Silva PMC, Wang P, Xu S, Kawano S, Sriswasdi S, Park SY, Grist TM, Buch V, Jantarabenjakul W, Wang W, Tak WY, Li X, Lin X, Kwon YJ, Quraini A, Feng A, Priest AN, Turkbey B, Glicksberg B, Bizzo B, Kim BS, Tor-Díez C, Lee CC, Hsu CJ, Lin C, Lai CL, Hess CP, Compas C, Bhatia D, Oermann EK, Leibovitz E, Sasaki H, Mori H, Yang I, Sohn JH, Murthy KNK, Fu LC, de Mendonça MRF, Fralick M, Kang MK, Adil M, Gangai N, Vateekul P, Elnajjar P, Hickman S, Majumdar S, McLeod SL, Reed S, Gräf S, Harmon S, Kodama T, Puthanakit T, Mazzulli T, de Lavor VL, Rakvongthai Y, Lee YR, Wen Y, Gilbert FJ, Flores MG, Li Q. Federated learning for predicting clinical outcomes in patients with COVID-19. Nat Med. 2021 Sep 15. doi: 10.1038/s41591-021-01506-3. Epub ahead of print. 
  8. Taher J, Mighton C, Chowdhary S, Casalino S, Frangione E, Arnoldo S, Bearss E, Binnie A, Bombard Y, Borgundvaag B, Chertkow H, Clausen M, Devine L, Faghfoury H, Friedman SM, Gingras AC, Khan Z, Mazzulli T, McGeer A, McLeod SL, Pugh TJ, Richardson D, Simpson J, Stern S, Strug L, Taher A, Lerner-Ellis J. Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study. BMJ Open. 2021 Sep 30;11(9):e052842. 

Triage and Flow (n=7)

  1. Javidan AP, Hansen K, Higginson I, Jones P, Ovens H, Lang E; IFEM Task Force on Emergency Department Crowding and Access Block. The International Federation for Emergency Medicine report on emergency department crowding and access block: a brief summary. Int J Emerg Med. 2021 Jan 14;14(1):4. 
  2. Javidan AP, Hansen K, Higginson I, Jones P, Ovens H, Lang E; IFEM Task Force on Emergency Department Crowding and Access Block. The International Federation for Emergency Medicine report on emergency department crowding and access block: a brief summary. Emerg Med Australas. 2021. Feb;33(1):161-163.
  3. Chartier LB, Ovens H, Hayes E, Davis B, Calder L, Schull M, Dreyer J, Ostrow O. Improving Quality of Care Through a Mandatory Provincial Audit Program: Ontario’s Emergency Department Return Visit Quality Program. Ann Emerg Med. 2021. Feb;77(2):193-202.
  4. Berthelot S, Breton M, Guertin JR, Archambault PM, Berger Pelletier E, Blouin D, Borgundvaag B, Duhoux A, Harvey Labbé L, Laberge M, Lachapelle P, Lapointe-Shaw L, Layani G, Lefebvre G, Mallet M, Matthews D, McBrien K, McLeod S, Mercier E, Messier A, Moore L, Morris J, Morris K, Ovens H, Pageau P, Paquette JS, Perry J, Schull M, Simon M, Simonyan D, Stelfox HT, Talbot D, Vaillancourt S. A value-based comparison of the management of ambulatory respiratory diseases in walk-in clinics, primary care practices, and emergency departments: Protocol for a multicenter prospective cohort study. JMIR Res Protoc. 2021 Feb 22;10(2):e25619. doi: 10.2196/25619. 
  5. McLeod SL, Grewal K, Thompson C, Thabane L, Borgundvaag B, Ovens H, Scott S, Ahmed T, Mittmann N, Worster A, Agoritsas T, Guyatt G. Influence of electronic triage decision-support on hospital admission, left without being seen and time to physician initial assessment in the emergency department. CJEM. 2021 Mar;23(2):214-218.
  6. Javidan AP, Hansen K, Higginson I, Jones P, Ovens H, Lang E; International Federation Emergency Department Crowding and Access Block Task Force. The International Federation for Emergency Medicine report on emergency department crowding and access block: A brief summary. Emerg Med J. 2021 Mar;38(3):245-246.
  7. Chartier LB, Jalali H, Seaton MB, Ovens H, Borgundvaag B, McLeod SL, Dainty KN, Ostrow O. Qualitative evaluation of a mandatory provincial programme auditing emergency department return visits. BMJ Open. 2021 Apr 7;11(4):e044218. doi: 10.1136/bmjopen-2020-044218.

Mild Traumatic Brain Injury (n=4)

  1. Blais Lécuyer J, Mercier É, Tardif PA, Archambault PM, Chauny JM, Berthelot S, Frenette J, Perry J, Stiell I, Émond M, Lee J, Lang E, McRae A, Boucher V, Le Sage N. S100B protein level for the detection of clinically significant intracranial haemorrhage in patients with mild traumatic brain injury: a subanalysis of a prospective cohort study. Emerg Med J. 2020. Dec 18;38(4):285-289.
  2. Beauchamp F, Boucher V, Neveu X, Ouellet V, Archambault P, Berthelot S, Chauny JM, de Guise E, Émond M, Frenette J, Lang E, Lee J, Mercier É, Moore L, Ouellet MC, Perry J, Le Sage N. Post-concussion symptoms in sports-related mild traumatic brain injury compared to non-sports-related mild traumatic brain injury. CJEM. 2021 Mar;23(2):223-231.
  3. Varner C, Thompson C, de Wit K, Borgundvaag B, Houston R, McLeod SL. Predictors of post-concussion syndrome in adults with acute mild traumatic brain injury presenting to the emergency department. CJEM. 2021. May;23(3):365-373
  4. Varner CE, Thompson C, de Wit K, Borgundvaag B, Houston R, McLeod SL. A randomized trial comparing prescribed light exercise to standard management for emergency department patients with acute mild traumatic brain injury. Acad Emerg Med. 2021 May;28(5):493-501.

Early Pregnancy (n=1)

  1. Dainty KN, Seaton MB, McLeod S, Tunde-Byass M, Tolhurst E, Rojas-Luengas V, Little D, Varner C. Reframing how early pregnancy loss is viewed in the emergency department. Qual Health Res. 2021 May;31(6):1119-1128.